Dutch-born Ghanaian international Derrick Luckassen secured Anderlecht’s qualification with a goal on Thursday.
The 24-year-old versatile defender scored his side’s third goal to send them through to the quarter finals of the Belgian Cup.
The hosts opened scoring in the 12th minute through Stipe Perica.
Kamer Roofe however, leveled things up eight minutes later for the away side before Ghanaian prodigy Jeremy Doku added to the advantage of the travelling team on the stroke of half time to make it 2-1.
Royal Excel Mouscron fought diligently in the early stages of the second half but couldn’t find the back of the net with their early pressure.
The former PSV Eindhoven made it 3-1 to Anderlecht in the 56th minute mark with a fine strike.
Cedric Omoigui meanwhile, managed to reduce his side’s deficit to 3-2 in the 79th minute.
Derrick Luckassen is eligible to feature for the Black Stars despite represent the Netherlands at the various youth levels.