Kwesi Donsu scored a late penalty to condemn Berekum Chelsea to their 15th defeat of the season during the closing week of the season.
Donsu made no mistakes from the spot four minutes from time to put his team ahead at the Akoon Park in Tarkwa.
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The win takes Medeama to 5th on the final league table on 54 points whilst Berekum Chelsea end the season at the 10th position on 43 points.
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