Gabonese head coach Patrice Neveu as well as defender Lloyd Palun and striker Kevin Mayi will not be involved on Friday night when the Panthers face the Black Stars in a Group C game.
Sportsworldghana.com can confirm that the trio have tested positive for Coronavirus and are now in isolation as nurses continue to attend to them.
The unavailability of Neveu and the the two players is a big blow for the side but they can count of Arsenal striker Pierre-Emerick Aubameyang who tested negative yesterday after being on isolation.
Gabon who won their first game by a lone goal against Comoros needs at least a draw to make qualification to the second round a certainty whereas Ghana must win the game if they hope to progress.