Obuasi Ashantigold SC were left in a deep pit by Yellow and Mauves lads at the Len Clay Stadium in Obuasi on Monday after in the Ghana Premier League.
Medeama SC defeated the Miners at their own backyard with a late winner to move 5th on the league table after 10 matches with 18 points and a game in hand.
Ashantigold on the other hand are on 14th place on the league table with 12 points from 11 games after winning just three games this season.
Both teams played with high intensity and created good openings in the first half but no goals were scored by the two teams.
Deep into additional time period of the frenetic and entertaining encounter, Ebenezer Ackahbi scored a last-gasp winner for the visitors.
Ashantigold will travel to face Kumasi Asante Kotoko SC in their next match as Medeama welcome Berekum Chelsea FC to the Akoon Park in Tarkwa.