Already relegated side Akyem Kotoku Royals FC on Sunday afternoon at the Theartre of Dreams in Dawu will hosts Karela United FC.
Karela United have been handed a major boost to stay in the Ghana Premier League after beating Bibiani Gold Stars FC 3-2 in their last game.
The have gone five games without a defeat with three draws and two wins from the five matches and needs to avoid defeat on the road to stay in the Ghana top-flight for another season.
Kotoku Royals beat Tamale City FC in their last game with an emphatic 4-1 victory to sink the Yellow and Blue side deep inside the relegation battle.
Karela beat Kotoku Royals 2-1 in their only meeting and would be praying for a win again to secure top-flight league for another season without depending on other results.
The Royals from Akyem would also be hoping for a win to end the season on a high.