Liverpool go looking for a fifth Premier League win in their last six in the competition on Tuesday night, but know even that isn’t now enough to overhaul Manchester City at the top of the table.
The Reds are relying on Aston Villa to take something off the reigning champions on the final day and they must then also win both their last.
Ghana’s Mohammed Salisu is as usual expected to start in central defence for the Saints tonight.
Southampton vs Liverpool predicted line-ups
Southampton’s predicted line-up (4-4-2):
GK Alex McCarthy; Kyle Walker-Peters, Jan Bednarek, Mohamed Salisu, Romain Perraud; Mohamed Elyounoussi, James Ward-Prowse, Oriol Romeu, Nathan Tella; Che Adams, Armando Broja.
Liverpool’s predicted line-up (4-3-3):
GK Alisson; Trent Alexander-Arnold, Joel Matip, Ibrahima Konate, Kostas Tsimikas; Naby Keita, Jordan Henderson, Thiago Alcantara; Diogo Jota, Sadio Mane, Luis Diaz.