Bibiani Gold Stars moved up the Ghana Premier League standings after Week 19 following their narrow home win against Medeama SC on Independence Day.
The home side needed an early goal at the start of the second half as Owusu Stephen Kaakyire scored in the 48th minute.
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The defeat is the sixth of the season for Medeama.
Gold Stars travel to Asante Kotoko next whilst Medeama play at home against Eleven Wonders.