Asante Kotoko take on Karela United on Wednesday during midweek of the Ghana Premier League counting for Week 30 of the competition this season.
Hearts of Oak do not play until Thursday when they take on Legon Cities meaning the Porcupine Warriors have another chance to go top of the league table after Wednesday to increase the pressure on their biggest rivals.
Both Hearts of Oak and Kotoko are on 53 points each after 29 games and a win for the team of Mariano Barreto takes them to 56 whilst the Phobians play a day later.
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The two biggest football clubs in the country will lock horns this Sunday during Week 31 of the season.